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oncogene    音标拼音: ['ɑŋkodʒ,in]
癌基因; 肿瘤基因

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  • Oncogene: What They Are What They Do - Cleveland Clinic
    An oncogene is a gene that may cause cancer It’s a mutated (changed) form of a normal gene, called a proto-oncogene, that manages cell growth When proto-oncogenes mutate into oncogenes, they cause cells to grow and divide uncontrollably Eventually, the abnormal cells may form tumors
  • Oncogenes, Tumor Suppressor Genes, and DNA Repair Genes
    When a proto-oncogene mutates (changes) or there are too many copies of it, it can become turned on (activated) when it is not supposed to be, at which point it's now called an oncogene When this happens, the cell can start to grow out of control, which might lead to cancer
  • Oncogene - National Human Genome Research Institute
    An oncogene is a mutated gene that has the potential to cause cancer Before an oncogene becomes mutated, it is called a proto-oncogene, and it plays a role in regulating normal cell division Cancer can arise when a proto-oncogene is mutated, changing it into an oncogene and causing the cell to divide and multiply uncontrollably
  • Definition of oncogene - NCI Dictionary of Cancer Terms
    When a proto-oncogene is changed so that too many copies are made or it becomes more active than normal, it is called an oncogene Oncogenes may cause normal cells to become cancer cells and grow in the body
  • Oncogene | Cancer, Genetics Molecular Biology | Britannica
    An oncogene is a sequence of deoxyribonucleic acid that has been altered or mutated from its original form, the proto-oncogene Operating as a positive growth regulator, the proto-oncogene is involved in promoting the differentiation and proliferation of normal cells
  • Oncogenes and tumor suppressor genes: functions and roles in cancers
    All cancers are rooted to mutations in oncogenes (OCGs) OCGs can be defined as a modified version of a proto‐OCG, a class of genes involved in normal cell division and growth but carry some deleterious mutations
  • What Is an Oncogene? Immunologists Rethink a Fundamental Cancer Concept
    These are normal cellular genes whose genetic code has become scrambled, leading to abnormal cell behavior The discovery of oncogenes helped to solidify the notion that cancer is a genetic disease, and opened the door to targeted treatment





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