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  • Pentose - an overview | ScienceDirect Topics
    The pentose can be either D-ribose as in ribonucleic acid (RNA) or 2-deoxyribose as in deoxyribonucleic acid (DNA) A nucleotide is a phosphate ester of a nucleoside The most common site of esterification is carbon No 5 of the pentose, this is referred to as a 5’ nucleotide
  • Pentose - an overview | ScienceDirect Topics
    The pentose phosphate pathway is the route by which pentose from food is metabolized Erythrose-4-P in some organisms is used as an intermediate in the synthesis of the aromatic ring of the amino acids D-xylulose formed in the glucuronic acid pathway, is further metabolized via the pentose phosphate pathway
  • Pentose - an overview | ScienceDirect Topics
    The pentose phosphate pathway is an important source of energy in many microorganisms Glucose can be oxidized with the liberation of electron pairs, which may enter an electron transport system However, its major role appears to be for biosynthesis
  • Pentose - an overview | ScienceDirect Topics
    Pentose-fermenting yeasts require a careful control for maintaining low oxygen levels in the culture medium needed for their oxidative metabolism Additionally, these yeasts successfully ferment pure xylose but not the aqueous hemicellulose streams generated during the biomass pretreatment, due to the presence of different inhibitors
  • Enzymes of glycolysis and the pentose phosphate pathway as targets of . . .
    In particular, the oxidative post-translational modification of the enzymes that participate in glycolysis and the pentose phosphate pathway (PPP) can modulate the carbon flux affecting synthesis of nucleotides, as well as production of adenosine triphosphate (ATP) and reducing equivalents (in the form of nicotinamide adenine dinucleotide
  • Pentose - an overview | ScienceDirect Topics
    Pentose phosphate pathway branches off glycolysis and is an alternative pathway of glucose metabolism (Gillies et al , 2008; Cairns et al , 2011) The NADPH and pentoses are generated in the pentose phosphate pathway
  • KRASG12D-driven pentose phosphate pathway remodeling imparts a . . .
    Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with an increasing incidence and a 5-year overall survival rate of only 12% 1 Although emerging immunotherapies and targeted treatments, such as pembrolizumab and olaparib, have been approved for PDAC treatment, their applicability is limited to rare molecular subtypes 2 KRAS G12D is the most common oncogenic mutation in
  • Pentose phosphate recycling driven by Gli1 contributes to chemotherapy . . .
    The Pentose phosphates Recycling is pivotal in helping glycolytic cancer cells meet their anabolic demands and combat oxidative stress Gli1 increases pyrimidine biosynthesis through stimulation of the Pentose phosphates Recycling, which leads to the accumulation of dCTP and may cause competitive inhibition of GEM activity in PDAC
  • Bioethanol production from pentose sugars: Current status and future . . .
    However, it does not have the ability of fermenting pentose sugars The most promising yeast species identified so far for the pentose fermentation are, C shehatae, P stipitis and P tannophilus [19], [20] Various studies have been carried out for the fermentation of xylose rich hydrolysates from different lignocellulosic materials (Table 1)





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