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glanders    
n. [兽医] 鼻疽病

[兽医] 鼻疽病

glanders
n 1: a destructive and contagious bacterial disease of horses
that can be transmitted to humans


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  • Clinical and Molecular Characterization of Human
    Burkholderia mallei is a gram-negative bacterium that causes glanders disease, which primarily affects equids B mallei can infect humans and cause clinical manifestations ranging from subclinical infections to severe conditions such as septicemia or pneumonia
  • Management of Accidental Laboratory Exposure to
    Glanders is a disease of equines caused by Burkholderia mallei, which appears to be a clone of B pseudomallei that has lost genetic material in association with a host-adapted parasitic existence The infection is now rare in horses in most parts of the world, and human infections, which may occur in those in close contact with infected
  • Laboratory-Acquired Human Glanders --- Maryland, May 2000
    In humans, glanders usually is acquired through direct skin or mucous membrane contact with infected animal tissues The incubation period usually is 1 to 14 days The clinical presentation varies (4,5); cutaneous inoculation can result in localized infection with nodule formation and lymphandenitis (4)
  • Etymologia: Glanders - Volume 21, Number 1—January 2015 - Emerging . . .
    Glanders [glanʹdərz] From the Old French glandres (“glands”) describing the enlargement of the parotid or submaxillary lymph nodes that is pathognomonic of the disease, glanders is a contagious disease of horses
  • Workshop on Treatment of and Postexposure Prophylaxis for
    For postexposure prophylaxis, recommended drugs are trimethoprim sulfamethoxazole or co-amoxiclav To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended
  • Natural Burkholderia mallei Infection in Dromedary, Bahrain
    We report natural B mallei infection in a dromedary that occurred during a glanders outbreak in horses Clinical signs as well as gross pathologic and microscopic lesions of the diseased dromedary were similar to changes seen in equids
  • Alfred Whitmore and the Discovery of Melioidosis
    The victim, however, had no history of recent animal exposure, and cultures yielded a bacterium that they recognized as different from what was then known as Bacillus mallei (now Burkholderia mallei), the cause of glanders, in its rapid luxuriant growth and motility
  • About Melioidosis - CDC
    Melioidosis is a bacterial infection in people and animals Melioidosis is spread through contact with contaminated soil, air, or water Cases may increase after hurricanes, heavy rain, and other severe weather events
  • Clinical and Molecular Characterization of Human Burkholderia mallei . . .
    Treating glanders disease is challenging because of B mallei’s resistance to many common antimicro-bial drugs A recent case from China highlighted initial therapy failure with levofloxacin and cefo-taxime sulbactam, but success was achieved by adding meropenem, doxycycline, and TMP SMX (11) In Iran, effective treatment involved imipen-
  • Molecular Typing of Burkholderia mallei Isolates from Equids with . . .
    glanders It is one of the most ancient diseases and is distributed worldwide B mallei infections are fre-quently reported in South America, the Middle East, South Asia, and some countries in Africa Equine glanders is a notifiable zoonotic disease; surveillance measures are enforced by the World Organisation for Animal Health (1)





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