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  • TYMP gene - MedlinePlus
    The TYMP gene provides instructions for making an enzyme called thymidine phosphorylase Learn about this gene and related health conditions
  • TYMP (gene) - Wikipedia
    TYMP encodes for the enzyme thymidine phosphorylase TYMP and thymidine phosphorylase are associated with angiogenesis, growth of endothelial cells, and mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)
  • TYMP Gene - GeneCards | TYPH Protein | TYPH Antibody
    TYMP (Thymidine Phosphorylase) is a Protein Coding gene Diseases associated with TYMP include Mitochondrial Dna Depletion Syndrome 1 and Mitochondrial Neurogastrointestinal Encephalomyopathy Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway
  • Thymidine phosphorylase: a potential new target for treating . . .
    We recently found that thymidine phosphorylase (TYMP), also known as platelet-derived endothelial cell growth factor, plays an important role in platelet activation in vitro and thrombosis in vivo by participating in multiple signaling pathways Platelets are a major source of TYMP
  • Entry - *131222 - THYMIDINE PHOSPHORYLASE; TYMP - OMIM - (OMIM. ORG)
    HGNC Approved Gene Symbol: TYMP The TYMP gene encodes thymidine phosphorylase (EC 2 4 2 4), a cytosolic enzyme that catalyzes the phosphorylation of thymidine or deoxyuridine to thymine or uracil, and is thus essential for the nucleotide salvage pathway (review by Suomalainen and Isohanni, 2010)
  • Thymidine phosphorylase facilitates retinoic acid inducible gene-I . . .
    We discovered a RIG-I dependent 7 gene signature that affects angiogenesis, inflammation and coagulation Among these, we identified the thymidine phosphorylase TYMP as a key mediator of RIG-I
  • A comprehensive pan-cancer analysis on the immunological role and . . .
    Our results indicated that TYMP was overexpressed and also significantly associated with a worse prognosis in several human cancers, such as kidney clear cell carcinoma (KIRC) and lower grade glioma (LGG) TYMP was also associated with TMB, MSI, and ICGs across a variety of malignancies
  • Targeting Thymidine Phosphorylase With Tipiracil Hydrochloride . . .
    Tipiracil hydrochloride (TPI), a selective TYMP inhibitor, has been approved by the Food and Drug Administration for clinical use We tested the hypothesis that TPI is a safe antithrombotic medication
  • Thymidine phosphorylase - Wikipedia
    Thymidine phosphorylase (EC 2 4 2 4) is an enzyme that is encoded by the TYMP gene and catalyzes the reaction: thymidine + phosphate thymine + 2-deoxy-alpha-D-ribose 1-phosphate Thymidine phosphorylase is involved in purine metabolism, pyrimidine metabolism, and other metabolic pathways
  • Mitochondrial neurogastrointestinal encephalopathy disease - MedlinePlus
    Variants (also called mutations) in the TYMP gene cause most cases of MNGIE disease The TYMP gene provides instructions for making an enzyme called thymidine phosphorylase Thymidine is a molecule known as a nucleoside After a chemical modification, thymidine is used as a building block of DNA





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