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  • Current state of biologics in treating eosinophilic esophagitis
    Eosinophilic esophagitis (EoE) is a chronic, allergen-mediated, eosinophil-predominant, type 2 inflammatory disease that progresses to fibrostenosis of the esophagus if left untreated This review focuses on biologics therapy in EoE
  • Biologics in the Treatment of Eosinophilic Esophagitis: Ready for Use . . .
    Eosinophilic esophagitis (EoE) is a chronic disease mediated by environmental allergens and type 2 immune inflammation, which causes significant symptoms including dysphagia and food impaction 1,2 The incidence and prevalence of EoE are rising and untreated disease can lead to significant esophageal stenosis 2,3 Standard treatments include proton-pump inhibitors (PPIs), swallowed topical
  • Biologics in eosinophilic esophagitis - PubMed
    Biologics for treatment of EoE may result in symptom and histologic improvement and has the potential to treat disease with minimal side effects Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the oesophagus whose incidence is on the rise Despite maximal use of guideline-based therapies including food elimination diets
  • Biologics for eosinophilic oesophagitis: a systematic review and meta . . .
    Keywords: Eosinophilic esophagitis, eosinophil gastrointestinal diseases, biologic therapies, meta-analysis KEY MESSAGES We performed a meta-analysis using high-quality randomized controlled trials to confirm the clinical efficacy and safety of biologic therapies
  • Biologics in Eosinophilic Esophagitis — Ready for Prime Time?
    Eosinophilic esophagitis is an immune-mediated, chronic, inflammatory disease of the esophagus that was first recognized as a distinct entity less than three decades ago 1 The immunopathogenesis of
  • Consumer’s Guide to Biologics for Eosinophilic Esophagitis
    5 Essential Facts About Biologics for Eosinophilic Esophagitis 1 The FDA has approved only one biologic to treat EoE That drug, dupilumab, is sold under the brand name Dupixent It is approved
  • Eosinophilic esophagitis: promising therapy, biomarkers, and assessment . . .
    Breakthroughs in biologic therapy for eosinophilic esophagitis Biologics and other novel therapies are needed for treatment of EoE because of suboptimal response rates to proton pump inhibitors (PPIs), most topical steroids, and dietary approaches, said Evan S Dellon MD, MPH, professor of medicine at University of North Carolina Chapel Hill
  • Current state of biologics in treating eosinophilic esophagitis
    Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory condition that interferes with normal food ingestion, negatively impacting quality of life (QoL) Treatment options include proton pump inhibitors, corticosteroids, biologics, or dietary elimination; however, ∼1 3 of patients remain insufficiently controlled
  • Biologics for eosinophilic oesophagitis: a systematic review . . . - PubMed
    Objective: Advancing the understanding of the pathophysiology of eosinophilic oesophagitis (EoE) and other eosinophilic gastrointestinal diseases (EGIDs) has spurred research into targeted biological therapies, while the conclusive therapeutic efficacy of biologics remains uncertain In this review, we conducted a meta-analysis of all RCTS of biologics in the treatment of EoE to evaluate their





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