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  • Immunization, Vaccines and Biologicals - World Health Organization (WHO)
    Polio vaccine, given multiple times, almost always protects a child for life The development of effective vaccines to prevent paralytic polio was one of the major medical breakthroughs of the 20th century There are six different vaccines to stop polio transmission: Inactivated polio vaccine (IPV) – protects against poliovirus types 1, 2, and 3
  • Safety profile of nOPV2 vaccine - World Health Organization (WHO)
    In less than a year, however, this first IPV was the centre of one the most serious vaccine safety events recorded, the Cutter incident, in which inadequate inactivation of the polio viruses during the manufacturing process resulted in 61 cases of vaccine-associated paralytic poliomyelitis (VAPP), 80 family contact cases, 17 community contact
  • FACT SHEET: VACCINE-DERIVED POLIOVIRUS - World Health Organization (WHO)
    OPV and IPV have important but distinct advantages, and both vaccines are necessary to end polio for good Because OPV protects both the individual and the community, it is essential to stop wild poliovirus transmission IPV is being introduced as part of preparations for OPV cessation and is vital to end polio once and for all
  • Recommendations to assure the quality, safety and efficacy of . . .
    In addition, WHO Guidelines for the safe production and quality control of poliomyelitis vaccines were adopted by the Committee in 2018 These Guidelines further align the biocontainment requirements for the production of both sIPV and IPV derived from wild-type strains (wIPV) with good manufacturing practices (GMP) and GAPIII requirements
  • Launching of the National Expansion for the Second Dose Inactivated . . .
    Committed to achieving the global eradication of Polio by 2026, Indonesia has undertaken comprehensive polio immunization efforts, offering the recommended doses of bivalent oral polio vaccine (bOPV) and inactivated poliovirus vaccine (IPV) to children before their first birthday Despite challenges posed by the COVID-19 pandemic, Indonesia continues to prioritize maintaining its WHO-declared
  • Recommendations to assure the quality, safety and efficacy of . . .
    The Requirements for inactivated poliomyelitis vaccine (IPV) were first formulated in 1959 (1) and revised in 1965 (2) Following several advances in vaccine production technology, the Requirements were further updated in 1981 (3) and amended in 1985 (4)
  • Immunization, Vaccines and Biologicals - World Health Organization (WHO)
    WHO Indonesia A child receiving oral polio drops After being declared polio-free by World Health Organization officials in 2014, Indonesia is observing National Polio Immunization Week by vowing to inoculate millions
  • History of polio vaccination - World Health Organization (WHO)
    Salk tested his experimental killed-virus vaccine on himself and his family in 1953, and a year later on 1 6 million children in Canada, Finland and the USA The results were announced on 12 April 1955, and Salk’s inactivated polio vaccine (IPV) was licensed on the same day
  • Training for the addition of a second dose of Inactivated Poliovirus . . .
    At the end of the module, the participant will be able to: Understand poliovirus transmission, poliomyelitis disease and global progress toward polio eradication Recognize the vaccines available against polio and the risks and benefits of each Describe the rationale for the addition of a second dose of IPV vaccine into the routine immunization schedule Available in both English and French
  • Circulating vaccine-derived poliovirus type 2 – Kenya
    On 11 July 2023, WHO received an official report regarding the detection of a circulating vaccine-derived poliovirus type 2 (cVDPV2) in two acute flaccid paralysis (AFP) cases and two asymptomatic healthy children community contacts from Hagadera refugee camp, in Kenya, the second largest refugee camp in the world with over 100 000 refugees The genetic sequencing analyses showed that all four





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