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  • Controversies in the Management of Central Nervous System . . .
    Central nervous system (CNS) coccidioidomycosis is predictably fatal if untreated [1, 2] and presents the clinician with multiple unique challenges [3] There are few studies to guide management, and experts often have differing approaches
  • Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal . . .
    We sought to evaluate the possible benefits of corticosteroids in a retrospective cohort of patients with CM as adjunctive therapy to antifungal treatment in those who experienced a CVA attributed to underlying CM-associated vasculitis This study was approved by the institutional review board of each institution
  • Central Nervous System Infections Due to Coccidioidomycosis
    Central nervous system (CNS) infection is an uncommon manifestation that is nearly always fatal if untreated The presentation is subtle, commonly with headache and decreased mentation The diagnosis should be considered in patients with these symptoms in association with a positive serum coccidioidal antibody test
  • Our Team | UC Davis Center for Valley Fever
    George R Thompson, M D , F I D S A Clinical Consultant, Coccidioidomycosis Serology Laboratory Co-Director, Center for Valley Fever Professor of Medicine Department of Medical Microbiology and Immunology Department of Medicine, Division of Infectious Diseases grthompson@ucdavis edu Research Program and Interests » Satya Dandekar, Ph D
  • Coccidioidal meningitis complicated by central nervous system . . .
    Prior to a 2014 retrospective study by Thompson et al , there were no clinical studies showing clear efficacy of steroid use in the management of coccidioidal meningitis, but rather only anecdotal evidence, case reports, and expert opinion
  • Controversies in the Management of Central Nervous System . . .
    Central nervous system infection with Coccidioides spp is fatal if untreated and complications occur even when therapy is directed by experienced clinicians We convened a panel of clinicians experienced in the management of coccidioidal meningitis to summarize current controversies and provide consensus for the management of this difficult
  • Isavuconazole in the Treatment of Coccidioidal Meningitis - PMC
    CNS involvement that causes meningitis is the most serious complication and carries significant morbidity and mortality (3) Current guidelines recommend high-dose fluconazole or itraconazole in the treatment of coccidioidal meningitis (1)
  • Routine CSF Analysis in Coccidioidomycosis Is Not Required
    Although routinely done, there has been no evaluation of the utility of performing routine cerebrospinal fluid (CSF) examination in patients with active coccidioidomycosis and high complement fixation (IgG) antibody titers or other risk factors for disseminated infection
  • Controversies in the Management of Central Nervous System . . .
    Central nervous system infection with Coccidioides spp is fatal if untreated and complications occur even when therapy is directed by experienced clinicians
  • Central Nervous System Coccidioidomycosis in Children: A . . . - PubMed
    CNS coccidioidomycosis is an uncommon and sometimes devastating complication of disseminated coccidioidomycosis Many patients present with relatively low CF titers and hydrocephalus is common





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