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  • Pemphigus Vulgaris: A Complete Overview - DermNet
    Pemphigus vulgaris is a rare autoimmune disease that is characterised by painful blisters and erosions on the skin and mucous membranes, most commonly inside the mouth It accounts for 70% of all pemphigus cases worldwide Images below show mucosal lesions
  • Pemphigus Foliaceus: Causes, Symptoms and Images - DermNet
    Pemphigus erythematosus (or Senear-Usher syndrome) is a variant of pemphigus foliaceus which shares clinical, histopathological, and serological features with systemic lupus erythematosus (SLE); they rarely coexist It accounts for 10% cases of all pemphigus disease
  • Paraneoplastic Pemphigus - DermNet
    Paraneoplastic pemphigus (PNP) is a rare, autoimmune, mucocutaneous, blistering disease that is almost always associated with a confirmed or occult neoplasm The cause of PNP is not completely understood
  • Bullous Pemphigoid: Causes, Symptoms, and Treatment - DermNet
    Bullous pemphigoid is the most common form of autoimmune subepidermal blistering disease Treatment for bullous pemphigoid is usually needed for several years In many cases, the pemphigoid eventually completely clears up, and the treatment can be stopped
  • Pemphigus - DermNet
    DermNet pages about pemphigus Benign familial pemphigus Brazilian pemphigus foliaceus Drug-induced pemphigus Endemic pemphigus foliaceus Familial benign pemphigus pathology IgA pemphigus Paraneoplastic pemphigus Paraneoplastic pemphigus pathology Pemphigus foliaceus Pemphigus foliaceus pathology Pemphigus vulgaris Pemphigus vulgaris images
  • IgA pemphigus - DermNet
    In SPD-type IgA pemphigus, the autoantigen is described as desmocollin 1, one of the desmosomal cadherins, the glycoproteins that maintain the shape of a cell In at least some cases of IEN-type IgA pemphigus, the autoantigens are desmoglein 1, desmoglein 3, and an unspecified transmembrane protein What is the differential diagnosis for IgA
  • Drug-induced pemphigus - DermNet
    Pemphigus may occur days, weeks, or as long as 6 months after the drug has been commenced Who gets drug-induced pemphigus? Over 200 cases of drug-induced pemphigus have been reported in the medical literature The reports suggest that patients with drug-induced pemphigus may have similar characteristics to non-drug-induced pemphigus
  • Hailey-Hailey disease (benign familial pemphigus) - DermNet
    Benign familial pemphigus usually appears in the second to fourth decade, although it can occur at any age It then tends to persist life-long It can affect people of all races What is the cause of benign familial pemphigus? Benign familial pemphigus is an inherited skin disorder, although occasionally sporadic cases arise without a family
  • Pemphigus vulgaris pathology - DermNet
    Pemphigus vulgaris is a chronic vesiculobullous skin disorder characterised by autoantibodies against desmoglein 3, which is a component of the desmosome (an intracellular adhesion molecule) Disruption of keratinocyte adhesion leads to superficial blistering and erosion affecting the skin and or mucous membranes Histology of pemphigus vulgaris
  • Pemphigus foliaceus pathology - DermNet
    IgA pemphigus: Typically there is a more prominent subcorneal neutrophilic infiltrate forming pustules When there is only minor vesicle formation the clue to this diagnosis is in the predominance of neutrophils Immunofluorescence show intercellular IgA deposition Differential diagnosis of pemphigus foliaceus





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