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  • mTOR - Wikipedia
    The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene
  • mTOR-what does it do? - PubMed
    Target of rapamycin (TOR) is a highly conserved serine threonine kinase that controls cell growth and metabolism in response to nutrients, growth factors, cellular energy, and stress TOR, which was originally discovered in yeast, is conserved in all eukaryotes including plants, worms, flies, and mammals
  • Multifaceted role of mTOR (mammalian target of rapamycin . . .
    The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and migration, to maintain
  • mTOR Signaling in Growth, Metabolism, and Disease - PMC
    mTOR is a serine threonine protein kinase in the PI3K-related kinase (PIKK) family that forms the catalytic subunit of two distinct protein complexes, known as mTOR Complex 1 (mTORC1) and 2 (mTORC2) (Fig 1A) mTORC1 is defined by its three core components: mTOR, Raptor (regulatory protein associated with mTOR), and mLST8 (mammalian lethal with
  • Where is mTOR and what is it doing there? | Journal of Cell . . .
    In mammals, mTOR is stimulated by nutrients and growth factors and inhibited by stress to ensure that cells grow only during favorable conditions Studies in different organisms have reported localization of TOR to several distinct subcellular compartments
  • MTOR gene - MedlinePlus
    The MTOR gene provides instructions for making a protein called mTOR This protein is found in various cell types throughout the body including brain cells It interacts with other proteins to form two distinct protein groups, called mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2)
  • mTOR Signaling in Growth, Metabolism, and Disease - Cell Press
    mTOR is a serine threonine protein kinase in the PI3K-related kinase (PIKK) family that forms the catalytic subunit of two distinct protein complexes, known as mTOR Complex 1 (mTORC1) and 2 (mTORC2) (Figure 1 A) mTORC1 is defined by its three core components: mTOR, Raptor (regulatory protein associated with mTOR), and mLST8 (mammalian lethal wi





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