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  • Identifying patients and clinical scenarios for use of long . . .
    To assess expert consensus on barriers and facilitators for long-acting injectable antipsychotic (LAI) use and provide clinical recommendations on issues where clinical evidence is lacking, including identifying appropriate clinical situations for LAI use
  • Identifying Profiles of Patients With Bipolar I Disorder Who . . .
    WHICH PATIENTS ARE GOOD CANDIDATES FOR LAI ANTIPSYCHOTICS? Many clinicians reserve injectable medications for patients with severe illness, multiple hospitalizations or medication trials, or well-established nonadherence
  • Clinical guideline recommendations for antipsychotic long . . .
    To review existing guidelines concerning antipsychotic use generally, and LAIs in particular, and how patients might be identified as potential candidates for LAI treatment Literature review Currently several first-generation and one second-generation antipsychotic LAIs are available, with others under development
  • A Practical Review of Long-Acting Injectable Antipsychotics
    Evidence from large studies suggests that LAI antipsychotics may be more effective for improving long-term clinical outcomes and are similar in tolerability to oral antipsychotics
  • Long-Acting Injectable Antipsychotics (LAIs) - PsychDB
    Long-Acting Injectable (LAI) Antipsychotics are antipsychotics delivered via intramuscular injection that can provide medication coverage from a period of weeks to months Once stabilized on an LAI, patients rarely will need oral antipsychotic supplementation
  • Long-Acting Injectable (LAI) Atypical Antipsychotics
    treatment are candidates for LAI Atypical Antipsychotic medications See LAI Atypical Antipsychotics Dosing Guide for information on individual agents Approval Criteria Initial Requests A preferred LAI Atypical Antipsychotic may be approved when ALL the following criteria are met: 1 Patient is ≥ 18 years old 2
  • 30. 3 Evidence for the Use of Long-Acting Injectable . . .
    Recent evidence shows that the use of long-acting injectable antipsychotic medications can improve outcomes after first-break psychosis Long-acting injectable antipsychotic medications have been shown to be more efficacious than oral antipsychotic medications in the treatment of schizophrenia





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