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  • GenomeQC: a quality assessment tool for genome assemblies and . . .
    Background Genome assemblies are foundational for understanding the biology of a species They provide a physical framework for mapping additional sequences, thereby enabling characterization of, for example, genomic diversity and differences in gene expression across individuals and tissue types Quality metrics for genome assemblies gauge both the completeness and contiguity of an assembly
  • Identification of constrained sequence elements across 239 . . .
    We combined the resulting contigs together with 52 previously published high-quality primate reference assemblies to create a reference-free whole-genome MSA of 239 primate species with Cactus 21
  • Advancing vertebrate genomics with long-read sequencing
    The recent emergence of long-read DNA sequencing technologies has enabled relatively simple, cheap and rapid assembly of near-complete genomes for diverse vertebrate species We are collaborating with numerous teams across the country to generate reference genomes for diverse Australian vertebrates, including mammals, reptiles and fish
  • Shark and ray genomics for disentangling their morphological . . .
    Whole genomes of more diverse shark and ray species are being sequenced by several projects affiliated with the global genome sequencing initiative Earth Biogenome Project (EBP) (Lewin et al , 2018), including the Vertebrate Genome Project (VGP) (Rhie et al , 2021), Fish 10K (Fan et al , 2020), and Darwin Tree of Life (https: www
  • Sequencing of the sea lamprey (Petromyzon marinus) genome . . .
    The lamprey genome provides an important resource for reconstructing vertebrate origins and the evolutionary events that have shaped the genomes of extant organisms
  • 100-My history of bornavirus infections hidden in vertebrate . . .
    Our analyses using ancient bornaviral sequences from over 100 vertebrate species genomes indicated that bornaviruses infected a broader range of host lineages during their long-term evolution than expected from extant bornaviral host ranges Our findings highlighted the hidden history of this RNA viral infection over geological timescales
  • Reference genome and demographic history of the most . . .
    management planning for this and other endangered species, we used the Vertebrate Genomes Project (VGP) pipeline to generate a chromosomal-level, haplotype-phased reference vaquita genome assembly that exceeds the “platinum-quality” reference standards established by the VGP (Rhie, McCarthy, et al , 2020) The VGP





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