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  • Lactate and lactylation: Behind the development of tumors
    Cancer Lett 2024 Jun 1:591:216896 doi: 10 1016 j canlet 2024 216896 Epub 2024 Apr 17 Authors Enci Dai 1 , Wei Wang 2 , Yingying Li 3 , Defeng Ye 4 , Yanli Li 5 Affiliations 1 Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China
  • Cancer Letters | Journal | ScienceDirect. com by Elsevier
    An international journal providing a forum for original and pertinent contributions in cancer research Cancer Letters is an international journal that considers full-length articles and Mini Reviews in the broad area of basic and translational oncology Additionally, Special Issues highlight topical areas in cancer research
  • 乳酸和乳酰化：肿瘤发展的背后,Cancer Letters - X-MOL
    Enci Dai 1 , Wei Wang 1 , Yingying Li 1 , Defeng Ye 2 , Yanli Li 1 Affiliation Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 Xinsongjiang Road, Shanghai, 201600, China
  • A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate . . .
    The allosteric regulation of pyruvate kinase M2 (PKM2) affects the switching of the PKM2 protein between the high-activity and low-activity states that allow ATP and lactate production, respectively PKM2, in its low catalytic state (dimeric form), is chiefly active in metabolically energetic cells, including cancer cells More recently, PKM2 has emerged as an attractive target due to its role
  • Issue 34 - The Cancer Letter
    In The Headlines: Increasing incidence of early-onset cancer is “a paradigm shift oncology isn’t quite prepared for” George Sigounas named the first-ever chief science advisor at NCI The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woes
  • Lactate and lactylation: Behind the development of tumors - Article . . .
    10 Lactate and lactylation: Behind the development of tumors; 10 Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells; 10 Epilepsy and psychosis; 10 Regulation of gene expression by glycolytic and gluconeogenic enzymes; 10 Transient Total Atrioventricular Block During Vein of Marshall Ethanolization for Atrial Fibrillation Ablation
  • Lactate and lactylation: Behind the development of tumors,Cancer . . .
    There is growing evidence that lactate can have a wide range of biological impacts in addition to being a waste product of metabolism Because of the Warburg effect, tumors generate lots of lactate, which create a tumor microenvironment (TME) with low nutrition, hypoxia, and low pH As a result, the immunosuppressive network is established to gain immune escape potential and regulate tumor growth
  • Lactate and lactylation: Behind the development of tumors
    Cancer Letters Volume 591, 1 June 2024, 216896 Lactate and lactylation: Behind the development of tumors Since lactate is an oxidizable substrate, it generates abundant ATP later on, providing energy for cancer proliferation In addition, high lactate levels inside and outside the cell can disrupt the acid-base balance in the body
  • Lactate and Lactylation: Behind the Development of Tumors - ResearchGate
    Download Citation | On Apr 1, 2024, Enci Dai and others published Lactate and Lactylation: Behind the Development of Tumors | Find, read and cite all the research you need on ResearchGate
  • Cancer Letters | Vol 591, 1 June 2024 - ScienceDirect
    Read the latest articles of Cancer Letters at ScienceDirect com, Elsevier’s leading platform of peer-reviewed scholarly literature select article RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination Enci Dai, Wei Wang, Yingying Li





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