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  • Catechol-O-methyltransferase - Wikipedia
    Catechol-O-methyltransferase (COMT; EC 2 1 1 6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure [7]
  • What Is the COMT Gene? And How Does It Affect Your Health?
    Chronically stressed? Can't shake the blues? It could be your genes! In part 2 of this series, learn about how the COMT gene can affect health and well-being
  • The Complete Guide to the COMT Mutation and Adrenal Fatigue
    The COMT gene helps make an essential enzyme known as catechol-O-methyltransferase This enzyme helps to degrade catecholamines like dopamine, norepinephrine, and epinephrine as well as drugs and substances that have the same catechol structure
  • COMT gene - MedlinePlus
    The COMT gene provides instructions for making an enzyme called catechol-O-methyltransferase Two versions of this enzyme are made from the gene The longer form, called membrane-bound catechol-O-methyltransferase (MB-COMT), is chiefly produced by nerve cells in the brain
  • COMT Gene Mutations: Symptoms, Test, and Treatment
    COMT mutations disrupt the breakdown of neurotransmitters, especially dopamine, resulting in mood swings, anxiety, and cognitive difficulties You can test for COMT mutations through genetic and DNA methylation tests
  • The COMT Gene: Decoding Its Role and Effects - ClarityX Blog
    In this blog, we will delve into the role of the COMT gene, its impact on dopamine, the health conditions associated with COMT, gene mutations, the pharmacogenomics of COMT, and the future directions of COMT research
  • Understanding COMT Mutations – a Comprehensive Guide
    This article will explore COMT mutations, their impact on our health, and how to manage them effectively What Is the COMT Gene? The COMT gene provides the blueprint for an enzyme also known as Catechol-O-methyltransferase This enzyme deactivates certain neurotransmitters, including dopamine, norepinephrine, and epinephrine
  • COMT Gene - GeneCards | COMT Protein | COMT Antibody
    COMT (Catechol-O-Methyltransferase) is a Protein Coding gene Diseases associated with COMT include Schizophrenia and Panic Disorder 1 Among its related pathways are Metapathway biotransformation Phase I and II and Neurotransmitter clearance
  • Effect of Catechol-O-Methyltransferase Genotype Polymorphism on . . .
    Different polymorphisms of the catechol-O-methyltransferase (COMT) gene affect the COMT enzyme activity The COMT enzyme plays a major role in the pathophysiology of various neurological and psychiatric disorders This review article aims to discuss





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