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  • Immunoglobulin M (IgM): Function, Tests Disorders - Cleveland Clinic
    IgM antibodies (immunoglobulins) are the first antibodies your immune system makes in response to an infection High IgM might mean you’ve had a recent infection Learn more about IgM antibodies, your immune system’s first responders to fight infections
  • Immunoglobulin M - Wikipedia
    Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates IgM is the first antibody to appear in the response to initial exposure to an antigen; [1][2] causing it to also be called an acute phase antibody
  • Immunoglobulin M (IgM) – Properties, Structure and Functions
    Immunoglobulin M (IgM), the largest pentameric immunoglobulin is used as a marker of recent primary infection for some diseases and can be produced in T independent manner which also aids in disease diagnosis IgM ELISA test can be performed to detect such antibodies in the serum of patients
  • Structure, Function, and Therapeutic Use of IgM Antibodies
    Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to foreign antigens
  • IgM: Structure, Function, and Clinical Significance in Immunity
    Immunoglobulin M (IgM) is a key component of the immune system, serving as one of the body’s initial defenses against infections It is often the first antibody produced in response to an antigen, making it essential for early-stage immunity
  • IgM Antibodies: Structure, Properties, and Functions
    IgM is the first immunoglobulin class produced in a primary response to an antigen IgM antibodies are relatively short-lived, disappearing earlier than IgG These early IgM antibodies have a low affinity as they are produced before B cells have undergone somatic hypermutation
  • Immunoglobulin M (IgM)- Structure and Functions - Microbe Notes
    IgM is the first immunoglobulin class to be synthesized by the neonate and plays a role in the pathogenesis of some autoimmune diseases Although IgM antibodies usually have low-affinity binding sites for antigen, they have ten combining sites per molecule that can synergize with each other
  • IgM: Key Player in Immunity and Disease Detection
    Immunoglobulin M (IgM) is a key component of the immune system, playing a role in defense mechanisms and disease detection As one of the first antibodies produced in response to infection, IgM serves as a marker for early-stage immune reactions Its presence can indicate recent exposure to pathogens, making it valuable in clinical diagnostics
  • Immunoglobulin M in Health and Diseases: How Far Have We Come and What . . .
    In this review, we explore how IgM structure and BCR signaling shapes B cell development, self and non-self-antigen-specific antibody responses, responses to infectious (such as viruses, parasites, and fungal) and non-communicable diseases (such as autoimmunity and allergic asthma)
  • IgM (Immunoglobulin M) Antibodies: Blood Test Levels
    Immunoglobulin M antibodies (IgM) are our first-line defense against a many infections can indicate of disease Learn more about high low IgM levels





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