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  • Brain-derived neurotrophic factor and its clinical implications
    Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory It is widely expressed in the CNS, gut and other tissues
  • BDNF Gene - GeneCards | BDNF Protein | BDNF Antibody
    BDNF (Brain Derived Neurotrophic Factor) is a Protein Coding gene Diseases associated with BDNF include Bulimia Nervosa and Obsessive-Compulsive Disorder Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Downstream signaling of activated FGFR2
  • Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on . . . - PubMed
    Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the healthy and diseased brain As a result, there is a large body of evidence that associates BDNF with neuronal maintenance, neuronal survival, plasticity, and neurotransmitter regulation
  • Neurobiology of BDNF in fear memory, sensitivity to stress . . . - Nature
    Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and
  • Brain-derived neurotrophic factor: a bridge between inflammation and . . .
    The neurotrophin brain-derived neurotrophic factor (BDNF) has emerged as crucial mediator of neuronal plasticity, since it is abundant in brain regions particularly relevant for plasticity, but also because it shows a remarkable activity-dependent regulation of expression and secretion (Bramham and Messaoudi, 2005), suggesting that it might
  • Brain Derived Neurotrophic Factor - an overview - ScienceDirect
    Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family and is known to play a role in brain plasticity (Hu and Russek, 2008) It is mainly synthesized by neurons and binds to the tropomyosin receptor kinase B (TrkB), triggering downstream BDNF TrkB signalling pathways
  • Establishment of Animal Models of Post-Traumatic Stress Disorder in . . .
    Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophic protein BDNF is distributed in a wide range of areas such as the central nervous system, peripheral nervous system, endocrine system, bone and cartilage tissue
  • BDNF gene therapy rescues neuronal function via unique and common . . .
    Brain-derived neurotrophic factor (BDNF) protects neurons from degeneration, making it a promising therapeutic target for Alzheimer's disease (AD) However, the genetic regulation resulting from BDNF overexpression in the brain remains to be further illustrated Using APP PS1 and rTg4510 mouse models, we analyzed hippocampal transcriptomes





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