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  • Botulinum toxin - Wikipedia
    Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species [23] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis [24] The toxin causes the disease
  • The Remarkable Story of Botox - Verywell Health
    Clostridium botulinum was first discovered by a Belgian scientist named Emile Pierre van Ermengem following a botulism outbreak in Belgium By the 1920s, scientists at the University of California, San Francisco, first tried to isolate the botulinum toxin
  • Early development history of Botox (onabotulinumtoxinA) - PMC
    The development of Botox (onabotulinumtoxinA) began in the 1970s as Dr Scott was attempting to identify an injectable substance that would weaken the extraocular eye muscles in patients with strabismus as an alternative to muscle surgery This search led to botulinum toxin type A, which was tested and developed over the next 15 years
  • The History Of Botox: A Complete Timeline - Bustle
    Fast-forward to the ’70s, and ophthalmologists first use that same toxin — a muscle-paralyzing neurotoxin we now know as Botox — to treat strabismus (crossed eyes)
  • The History of Botulinum Toxins in Medicine: A . . . - PubMed
    Botulinum toxin was first approved by the US Food and Drug Administration in 1989 for the treatment of blepharospasm and strabismus, but the history starts long before this, with outbreaks of food poisoning in the tenth century
  • History of Botox From Toxin to Blockbuster Medical and Beauty . . .
    Botox, the pharmaceutical drug best known for smoothing out wrinkles, took more than a decade to reach its potential On Tuesday, pharmaceutical giant AbbVie said it's acquiring Allergan, the
  • The Real History Behind the Birth of Botox | Readers Digest
    In 1987, Vancouver doctors Jean and Alastair Carruthers accidentally discovered cosmetic properties in a toxin normally used by ophthalmologists The couple’s discovery changed the face of beauty—and later became a billion-dollar industry
  • The 200-Year Timeline on Botulinum Toxin: From Biologic . . .
    The history of botulinum toxin dates back to the late 1700s, when food preparation, storage, and later canning practices led to outbreaks of botulism across Europe and the United States
  • History and Evolution of Botox as a Medical Aesthetic Treatment
    Botox, derived from botulinum toxin, has a fascinating history that spans over two centuries Initially identified in the early 1800s by German physician Justinus Kerner, the toxin was linked to cases of food poisoning
  • A brief history of Botox - Dazed
    First introduced on the market in 1989, the original injectable has become ubiquitous for its ability to “freeze” faces and hold back time – or at least look like it In the decades since its introduction, Botox has quite literally changed the face of humanity





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