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  • Checking your browser - reCAPTCHA - PubMed
    Checking your browser before accessing pubmed ncbi nlm nih gov Click here if you are not automatically redirected after 5 seconds
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    Pognan F, Beilmann M, Boonen HCM, Czich A, Dear G, Hewitt P, Mow T, Oinonen T, Roth A, Steger-Hartmann T, Valentin JP, Van Goethem F, Weaver RJ, Newham P Nat Rev Drug Discov, 22 (4):317-335, 13 Feb 2023 Cited by: 7 articles | PMID: 36781957 | PMCID: PMC9924869 Review Free to read use
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    Development of targeted protein degradation therapeutics PROTAC targeted protein degraders: the past is prologue Proteolysis-targeting chimeras in drug development: A safety perspective Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
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    Here, we investigated the utility of hepatic-, cardiac-, and kidney-derived cell lines to (1) accurately predict cytotoxicity and (2) to accurately predict specific organ toxicities
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    Valvular heart disease associated with fenfluramine-phentermine Appetite suppressants and valvular heart disease Evidence for possible involvement of 5-HT (2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications
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    A target safety assessment of the potential toxicological risks of targeting plasmepsin IX X for the treatment of malaria Barber J, Sikakana P, Sadler C, Baud D, Valentin JP, Roberts R Toxicol Res (Camb), 10 (2):203-213, 15 Feb 2021 Cited by: 2 articles | PMID: 33884171 | PMCID: PMC8045587 Review Free to read
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    In this article, we first summarize the key goals of investigative toxicology and highlight the current approaches used in investigative toxicology using published case studies, mainly from across the group of companies surveyed
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    1 Department of Physical Education and Sport, University of the Basque Country UPV EHU, Vitoria-Gasteiz Spain This review aimed to determine the ideal combination of post activation potentiation (PAP) strategies for an improved strength performance After analysing 202 articles, 15 studies met the inclusion criteria
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    Lipopolysaccharides, but not Angiotensin ll, lnduces Direct Pro-lnflammatory Effects in Cultured Mouse Arteries and Human Endothelial and Vascular Smooth Muscle Cells Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance-sized arteries
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    Methods: We summarized the strength of evidence and extent of potential biases in the published literature of psychological interventions for pain treatment using a range of criteria, including the statistical significance of the random effects summary estimate and of the largest study of each meta-analysis, number of participants, 95% predictio





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